Open-access commentary by Mir N. and Sagar S. (June 2025) on amputee rehabilitation at a Level I trauma centre in India, where more than 23,500 new amputations are recorded each year. The authors argue for tightly coordinated multidisciplinary teams — surgeons, physiotherapists, psychologists, social workers — and make the case that early rehabilitation is the single biggest lever on long-term function and quality of life. Systemic barriers covered include delayed hospital arrival, out-of-pocket costs, and limited prosthesis availability, alongside completed and ongoing trials at the centre spanning surgical technique to psychological intervention.